Gene information
Official symbol DLC1
Official full name DLC1 Rho GTPase activating protein
Gene type protein-coding gene
Chromosome8p22
Alias symbolHP; ARHGAP7; STARD12; DLC-1; p122-RhoGAP
Gene familyRho GTPase activating proteins; StAR related lipid transfer domain containing
Resources
Entrez Gene 10395
HGNC HGNC:2897
Ensembl ENSG00000164741
Vega OTTHUMG00000090825
UCSC uc003wwm.3
GO terms: 77 records
GO Description Category LogP Number of genes Detail
GO:0001838 embryonic epithelial tube formation GO Biological Processes -6.74209917 20 More
GO:0001841 neural tube formation GO Biological Processes -5.20987525 16 More
GO:0001843 neural tube closure GO Biological Processes -4.06290305 13 More
GO:0001952 regulation of cell-matrix adhesion GO Biological Processes -7.29794194 21 More
GO:0001953 negative regulation of cell-matrix adhesion GO Biological Processes -4.47602531 9 More
GO:0002009 morphogenesis of an epithelium GO Biological Processes -21.4354199 71 More
GO:0003007 heart morphogenesis GO Biological Processes -18.8519524 49 More
GO:0005925 focal adhesion GO Cellular Components -8.40302345 46 More
GO:0005938 cell cortex GO Cellular Components -2.49954036 24 More
GO:0006919 activation of cysteine-type endopeptidase activity involved in apoptotic process GO Biological Processes -5.45408545 14 More
GO:0007162 negative regulation of cell adhesion GO Biological Processes -21.5212108 58 More
GO:0007420 brain development GO Biological Processes -11.5572036 75 More
GO:0007507 heart development GO Biological Processes -29.3002557 91 More
GO:0008285 negative regulation of cell population proliferation GO Biological Processes -53.5569125 147 More
GO:0008289 lipid binding GO Molecular Functions -15.8223476 88 More
GO:0008360 regulation of cell shape GO Biological Processes -5.20319448 20 More
GO:0009792 embryo development ending in birth or egg hatching GO Biological Processes -12.9988944 72 More
GO:0010639 negative regulation of organelle organization GO Biological Processes -2.25995266 25 More
GO:0010810 regulation of cell-substrate adhesion GO Biological Processes -12.3653476 37 More
GO:0010812 negative regulation of cell-substrate adhesion GO Biological Processes -8.89322529 17 More
GO:0010942 positive regulation of cell death GO Biological Processes -48.7037743 123 More
GO:0010950 positive regulation of endopeptidase activity GO Biological Processes -13.2452311 34 More
GO:0010952 positive regulation of peptidase activity GO Biological Processes -14.1524623 37 More
GO:0014020 primary neural tube formation GO Biological Processes -5.01152693 15 More
GO:0016331 morphogenesis of embryonic epithelium GO Biological Processes -7.49308957 23 More
GO:0019904 protein domain specific binding GO Molecular Functions -3.48133193 23 More
GO:0021915 neural tube development GO Biological Processes -7.57225811 24 More
GO:0022604 regulation of cell morphogenesis GO Biological Processes -5.63620747 32 More
GO:0030029 actin filament-based process GO Biological Processes -9.62516039 61 More
GO:0030036 actin cytoskeleton organization GO Biological Processes -5.67075265 47 More
GO:0030055 cell-substrate junction GO Cellular Components -9.04790297 48 More
GO:0030155 regulation of cell adhesion GO Biological Processes -41.8400792 131 More
GO:0030695 GTPase regulator activity GO Molecular Functions -1.46750739 13 More
GO:0030900 forebrain development GO Biological Processes -11.1545964 48 More
GO:0030902 hindbrain development GO Biological Processes -2.77508929 8 More
GO:0031252 cell leading edge GO Cellular Components -1.97716247 28 More
GO:0031589 cell-substrate adhesion GO Biological Processes -10.7590108 32 More
GO:0032231 regulation of actin filament bundle assembly GO Biological Processes -4.42971140 15 More
GO:0032956 regulation of actin cytoskeleton organization GO Biological Processes -4.25470878 32 More
GO:0032970 regulation of actin filament-based process GO Biological Processes -7.72273150 43 More
GO:0034329 cell junction assembly GO Biological Processes -3.18336526 12 More
GO:0034330 cell junction organization GO Biological Processes -7.96624809 49 More
GO:0035148 tube formation GO Biological Processes -7.32029616 23 More
GO:0035239 tube morphogenesis GO Biological Processes -44.2569269 123 More
GO:0035306 positive regulation of dephosphorylation GO Biological Processes -3.01689914 9 More
GO:0040013 negative regulation of locomotion GO Biological Processes -30.7871461 81 More
GO:0042169 SH2 domain binding GO Molecular Functions -2.48632122 4 More
GO:0043009 chordate embryonic development GO Biological Processes -11.8113315 68 More
GO:0043065 positive regulation of apoptotic process GO Biological Processes -46.1285536 112 More
GO:0043068 positive regulation of programmed cell death GO Biological Processes -46.5713594 114 More
GO:0043281 regulation of cysteine-type endopeptidase activity involved in apoptotic process GO Biological Processes -14.7594418 39 More
GO:0044853 plasma membrane raft GO Cellular Components -18.4542052 33 More
GO:0045121 membrane raft GO Cellular Components -30.0775030 71 More
GO:0046578 regulation of Ras protein signal transduction GO Biological Processes -3.44587232 19 More
GO:0048598 embryonic morphogenesis GO Biological Processes -22.1253699 83 More
GO:0048729 tissue morphogenesis GO Biological Processes -31.7796969 96 More
GO:0051056 regulation of small GTPase mediated signal transduction GO Biological Processes -3.71798673 14 More
GO:0051058 negative regulation of small GTPase mediated signal transduction GO Biological Processes -1.97647557 4 More
GO:0051129 negative regulation of cellular component organization GO Biological Processes -13.1016989 75 More
GO:0051345 positive regulation of hydrolase activity GO Biological Processes -19.7369783 79 More
GO:0051492 regulation of stress fiber assembly GO Biological Processes -3.91249954 13 More
GO:0051493 regulation of cytoskeleton organization GO Biological Processes -3.52271067 40 More
GO:0051494 negative regulation of cytoskeleton organization GO Biological Processes -1.98331572 7 More
GO:0060322 head development GO Biological Processes -11.995356 79 More
GO:0060562 epithelial tube morphogenesis GO Biological Processes -17.7630248 53 More
GO:0060589 nucleoside-triphosphatase regulator activity GO Molecular Functions -1.46750739 13 More
GO:0060606 tube closure GO Biological Processes -4.01197458 13 More
GO:0072175 epithelial tube formation GO Biological Processes -6.28242122 20 More
GO:0098857 membrane microdomain GO Cellular Components -30.8181788 72 More
GO:0110020 regulation of actomyosin structure organization GO Biological Processes -4.68299748 15 More
GO:0110053 regulation of actin filament organization GO Biological Processes -3.93783734 26 More
GO:1901888 regulation of cell junction assembly GO Biological Processes -8.71146171 30 More
GO:1901889 negative regulation of cell junction assembly GO Biological Processes -5.33337113 9 More
GO:1902532 negative regulation of intracellular signal transduction GO Biological Processes -29.4927428 92 More
GO:1902903 regulation of supramolecular fiber organization GO Biological Processes -5.63791156 37 More
GO:1902904 negative regulation of supramolecular fiber organization GO Biological Processes -2.83678359 16 More
GO:2000116 regulation of cysteine-type endopeptidase activity GO Biological Processes -14.4496812 41 More
Related study: 1 record
Molecular factor Omics type Application Objective MI type Reference
cg10090985 hypermethylation epigenomics myocardial infarction[diagnosis] myocardial infarction Rask-Andersen M et al. Hum Mol Genet. 2016
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